Diet Pepsi Calories & Nutrition Facts (12 oz Can)

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Diet Pepsi has 0 calories, 0g sugar, 0g carbs and 35mg sodium in a 12 fl oz can, plus about 35mg of caffeine. It is sweetened with aspartame and acesulfame potassium, so it adds no carbohydrate and does not raise blood sugar directly. Regular Pepsi has about 150 calories and 41g sugar in the same can.

Quick Nutrition Facts

Per 1 can (12 fl oz, 355 mL)

Nutrient	Amount
Calories	0 kcal
Protein	0g
Carbohydrates	0g
Fiber	0g
Sugars	0g
Fat	0g
Sodium	35 mg

Macronutrient Breakdown

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NUTRITIONIST'S INSIGHT

A can of Diet Pepsi adds nothing to your calorie or carb count, which makes it an easy swap for regular cola if the goal is cutting added sugar. The tradeoffs are small: about 35mg of caffeine (roughly a third of a cup of coffee), 35mg of sodium, and phosphoric acid, which is hard on tooth enamel if you sip all day. The WHO's 2023 guideline advises against relying on non-sugar sweeteners for long-term weight control, so treat it as a bridge away from sugary drinks and not as your main source of hydration.

Myth Busters

MYTH #1: Diet Pepsi spikes blood sugar like regular Pepsi

TRUTH: The label shows 0g carbohydrate and 0g sugar per can, so there is nothing for the body to convert into glucose. Regular Pepsi carries about 41g of sugar per 12 fl oz can. Diet Pepsi: Nutrition Facts & Ingredients

MYTH #2: Aspartame in diet soda is proven to cause cancer

TRUTH: In July 2023 IARC classified aspartame as possibly carcinogenic (Group 2B) based on limited evidence, while JECFA kept the acceptable daily intake at 40 mg per kg of body weight. The FDA says it found no safety concerns at current levels of use. Aspartame hazard and risk assessment results released; Aspartame and Other Sweeteners in Food

MYTH #3: Zero-calorie soda guarantees weight loss

TRUTH: The WHO's 2023 guideline found no long-term body-fat benefit from non-sugar sweeteners in adults or children and advises against using them for weight control. Swapping a sugary soda for Diet Pepsi cuts calories that day, but does not guarantee weight loss. WHO advises not to use non-sugar sweeteners for weight control; WHO guideline on the use of non-sugar sweeteners

MYTH #4: Diet Pepsi has no caffeine

TRUTH: A 12 fl oz can contains about 35mg of caffeine. PepsiCo sells a separate Caffeine Free Diet Pepsi with the same zero calories. Diet Pepsi: Nutrition Facts & Ingredients; PepsiCo Product Facts: Caffeine

NutriScore by Health Goals

Health Goal	NutriScore	Why This Score?
Weight Loss		Zero calories per can makes it a useful replacement for a 150-calorie regular cola. The grade stops at B because the WHO found no long-term weight benefit from sweeteners and it supplies no satiety. Diet Pepsi: Nutrition Facts & Ingredients; WHO advises not to use non-sugar sweeteners for weight control
High Protein		0g protein per can. It contributes nothing toward a protein target. Diet Pepsi: Nutrition Facts & Ingredients
Low Carb / Keto		0g carbs and 0g sugar per can, so it fits any carb limit including strict keto. Diet Pepsi: Nutrition Facts & Ingredients
Heart Health		Only 35mg of sodium and no fat, but the WHO guideline flags possible long-term cardiovascular associations with regular sweetener use, based on observational data. Diet Pepsi: Nutrition Facts & Ingredients; WHO advises not to use non-sugar sweeteners for weight control
Diabetes Management		No carbohydrate means no direct glucose load, so it is a better choice than regular cola. The WHO guideline excludes people with existing diabetes from its recommendation against sweeteners. Diet Pepsi: Nutrition Facts & Ingredients; WHO advises not to use non-sugar sweeteners for weight control
Nutrient Density		No vitamins, fiber, protein or meaningful minerals. Diet Pepsi: Nutrition Facts & Ingredients

PERSONALIZED NUTRITION

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Blood Sugar Response - Diet Pepsi (1 can / 355 mL)

With 0g carbohydrate and 0g sugar, Diet Pepsi gives the body no glucose to absorb, so a healthy adult's blood sugar stays near its fasting baseline for the full 2-hour window. Any small movement comes from the rest of the meal, not the can. Diet Pepsi: Nutrition Facts & Ingredients; WHO advises not to use non-sugar sweeteners for weight control

Estimated Blood Glucose Response (mg/dL)

Illustrative baseline for a healthy adult drinking one can on its own. Meals eaten with it, and individual insulin sensitivity, change the real curve.

How to flatten the spike

Count it as 0g carbs when logging, and carb-count the food you drink it with.
Drink it with a meal that has protein and fiber so the meal's carbs rise more slowly.
Replace sugary drinks with it rather than adding it on top of them.
Alternate with water or sparkling water to keep total sweet-taste exposure down.

Cultural Significance

PepsiCo introduced Diet Pepsi nationally in the US in 1964 as a sugar-free answer to Diet Rite and Tab, and it became the number two diet cola behind Diet Coke. It is a staple order in fast-food restaurants, vending machines and convenience stores in the US and many other markets, often as a lower-sugar swap where soft drinks carry a sugar tax.

Compare & Substitute

Diet Pepsi vs Similar Foods

Nutrient	Pepsi Original (12 fl oz)	Pepsi Zero Sugar (12 fl oz)	Diet Coke (12 fl oz)	Plain sparkling water (12 fl oz)
Calories	150 kcal	0 kcal	0 kcal	0 kcal
Protein	0g	0g	0g	0g
Carbohydrates	41g	0g	0g	0g
Fat	0g	0g	0g	0g

Frequently Asked Questions

How many calories are in Diet Pepsi?

A 12 fl oz can has 0 calories, 0g sugar and 0g carbohydrate according to the US label. Larger bottles keep zero calories; sodium and caffeine scale with volume.

Does Diet Pepsi have caffeine?

Yes, about 35mg per 12 fl oz can, roughly a third of a cup of brewed coffee. Choose Caffeine Free Diet Pepsi if you want none.

What sweeteners are in Diet Pepsi?

The US formulation uses aspartame and acesulfame potassium, and carries a phenylketonuria warning. Some regional or retailer listings name sucralose instead, so check the can you are buying.

Can I drink Diet Pepsi with diabetes?

It contains no carbohydrate, so it does not raise blood glucose directly and fits carb-counting plans as 0g. The WHO's sweetener guideline does not apply to people with pre-existing diabetes. Ask your care team about daily limits if you drink several a day.

Is aspartame in Diet Pepsi safe?

JECFA reaffirmed an acceptable daily intake of 40 mg per kg of body weight in 2023, and IARC listed aspartame as possibly carcinogenic (Group 2B) on limited evidence. The FDA says it did not find safety concerns at current levels of use.

Is Diet Pepsi better than regular Pepsi?

For calories and sugar, yes: 0 versus about 150 calories and 0g versus 41g sugar per 12 fl oz can. Both are acidic and contain caffeine, so tooth wear is not much different.